Hexamethyldisilazane
Product identifier
- Product name: Hexamethyldisilazane
- CBnumber: CB9105784
- CAS: 999-97-3
- EINECS Number: 213-668-5
- Synonyms: HMDS,Hexamethyldisilazane
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: Hexamethyldisilazane
- Synonyms: HMDS,Hexamethyldisilazane
- CAS: 999-97-3
- EC number: 213-668-5
- MF: C6H19NSi2
- MW: 161.39
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Nitrogen oxides (NOx) silicon oxides
Flash back possible over considerable distance., Container explosion may occur under fire conditions.
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Further information
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 1 | Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride) | |
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 1 | Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Environmental precautions
Do not let product enter drains. Risk of explosion.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb?). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Handle under nitrogen, protect from moisture. Store under nitrogen.
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition. Keep locked up or in an area accessible only to qualified or authorized persons.
Hydrolyzes readily.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentUse equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm Break through time: 480 min
Material tested:Camatril? (KCL 730 / Aldrich Z677442, Size M)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Splash contact Material: Chloroprene
Minimum layer thickness: 0,65 mm Break through time: 240 min Material tested:KCL 720 Camapren?
Flame retardant antistatic protective clothing.
Recommended Filter type: Filter type K
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- Appearancecolorless liquid, clear
- OdourNo data available
- Odour ThresholdNo data available
- pH>7,0
- Melting point/freezing pointMelting point/range: -76,2 °C at 1.013 hPa
- Initial boiling point and boiling range 125 °C
- Flash point11,4 °C - closed cup
- Evaporation rateNo data available
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 16,3 %(V) Lower explosion limit: 0,8 %(V)
- Vapour pressure 19 hPa at 20 °C
- Vapour density 4.6 (vs air)
- Relative density0,77 at 20 °C
- Water solubilityinsoluble
- Partition coefficient: n-octanol/waterlog Pow: 2,62
- Autoignition temperature 380,0 °C
- Decomposition temperatureNo data available
- ViscosityViscosity, kinematic: 0,9 mm2/s at 20 °C Viscosity, dynamic: No data available
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
Other safety information
No data available
Reactivity
Vapors may form explosive mixture with air.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) . Hydrolyzes readily.
Possibility of hazardous reactions
No data available
Conditions to avoid
Ammonia is formed upon contact with water or humid air. Warming.
Incompatible materials
Strong oxidizing agents, Strong acids
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityLC50 Inhalation - Rat - male and female - 6 h - 10 mg/l (OECD Test Guideline 403)
LD50 Dermal - Rabbit - male and female - 547 - 589 mg/kg (OECD Test Guideline 402)
Result: No eye irritation (OECD Test Guideline 405)
S. typhimurium Result: negative
Toxicity
static test EC50 - Daphnia magna (Water flea) - 80 mg/l - 48 h (Directive 67/548/EEC, Annex V, C.2.)
Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 15,3 % - Not readily biodegradable. (Directive 67/548/EEC Annex V, C.4.E.)
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
UN number
ADR/RID: 1992 IMDG: 1992 IATA: 1992
UN proper shipping name
ADR/RID: FLAMMABLE LIQUID, TOXIC, N.O.S. (1,1,1,3,3,3-hexamethyldisilazane) IMDG: FLAMMABLE LIQUID, TOXIC, N.O.S. (1,1,1,3,3,3-hexamethyldisilazane)
IATA: Flammable liquid, toxic, n.o.s. (1,1,1,3,3,3-hexamethyldisilazane)
Transport hazard class(es)
ADR/RID: 3 (6.1) IMDG: 3 (6.1) IATA: 3 (6.1)
Packaging group
ADR/RID: II IMDG: II IATA: II
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- CAS: Chemical Abstracts Service
- EC50: Effective Concentration 50%
- IATA: International Air Transportation Association
- IMDG: International Maritime Dangerous Goods
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- STEL: Short term exposure limit
- TWA: Time Weighted Average
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.