Dichloroacetic acid
Product identifier
- Product name: Dichloroacetic acid
- CBnumber: CB5671951
- CAS: 79-43-6
- EINECS Number: 201-207-0
- Synonyms: Dichloroacetic acid,2,2-dichloroacetic acid
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: Dichloroacetic acid
- Synonyms: Dichloroacetic acid,2,2-dichloroacetic acid
- CAS: 79-43-6
- EC number: 201-207-0
- MF: C2H2Cl2O2
- MW: 128.94
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Hydrogen chloride gas Combustible.
Vapors are heavier than air and may spread along floors. Risk of dust explosion.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Further information
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb?). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Tightly closed. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.
Storage stability
Recommended storage temperature 2 - 8 °C
Handle and store under inert gas.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentUse equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Full contact Material: Viton?
Minimum layer thickness: 0,7 mm Break through time: 480 min
Material tested:Vitoject? (KCL 890 / Aldrich Z677698, Size M)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please
contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Splash contact Material: Chloroprene
Minimum layer thickness: 0,65 mm Break through time: 120 min Material tested:KCL 720 Camapren?
Acid-resistant protective clothing
Recommended Filter type: Filter A (acc. to DIN 3181) for vapours of organic compounds
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Do not let product enter drains.
Information on basic physicochemical properties
- Appearancecolorless clear, liquid
- Odourpungent
- Odour ThresholdNo data available
- pH1,2 at 129 g/l at 20 °C
- Melting point/freezing pointMelting point/range: 9 - 11 °C - lit.
- Initial boiling point and boiling range 194 °C - lit.
- Flash point113 °C - closed cup
- Evaporation rateNo data available
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limitsNo data available
- Vapour pressure 0,19 hPa at 20 °C
- Vapour density 4,45 - (Air = 1.0)
- Relative density1,56 at 20 °C
- Water solubilitysoluble
- Partition coefficient: n-octanol/waterlog Pow: 0,92 - (Lit.), Bioaccumulation is not expected.
- Autoignition temperatureNo data available
- Decomposition temperatureNo data available
- ViscosityViscosity, kinematic: 4,696 mm2/s at 20 °C2,716 mm2/s at 40 °C Viscosity, dynamic: No data available
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
Other safety information
Relative vapor density
4,45 - (Air = 1.0)
Reactivity
Forms explosive mixtures with air on intense heating.
A range from approx. 15 Kelvin below the flash point is to be rated as critical.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
Risk of explosion with:
furfuryl alcohol
Violent reactions possible with:
Amines Bases
Strong oxidizing agents strong reducing agents Sulfur compounds
Risk of ignition or formation of inflammable gases or vapours with:
Metals mercaptans
Exothermic reaction with:
Water
Conditions to avoid
Strong heating.
Incompatible materials
Gives off hydrogen by reaction with metals.
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityLD50 Dermal - Rabbit - 797 mg/kg Remarks: (ECHA)
Result: Causes severe burns. Remarks: (RTECS)
Result: Causes serious eye damage. Remarks: (RTECS)
Causes serious eye damage.
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476
Result: negative
Test Type: Ames test
Test system: Escherichia coli/Salmonella typhimurium Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471
Result: negative
Test Type: Chromosome aberration test in vitro Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 473
Result: negative
Test Type: Transgenic rodent somatic cell gene mutation assay Species: Mouse
Cell type: Liver cells Application Route: Oral
Result: negative Remarks: (ECHA)
Test Type: Micronucleus test Species: Rat
Cell type: Bone marrow Application Route: Oral
Method: OECD Test Guideline 475 Result: negative
May damage fertility. Studies indicating a hazard to babies during the lactation period
Toxicity
No data available
EC50 - Daphnia magna (Water flea) - 106 mg/l - 24 h Remarks: (ECOTOX Database)
Persistence and degradability
Biodegradability aerobic - Exposure time 15 d
Result: 93 % - Readily biodegradable. (OECD Test Guideline 301F)
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
Very toxic to aquatic life.
Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
IncompatibilitiesDCA is a medium strong acid; incompatible with nonoxidizing mineral acids; organic acids; bases, acrylates, aldehydes, alcohols, alkylene oxides; ammonia, aliphatic amines; alkanolamines, aromatic amines; amides, furfuryl alcohol (explosion hazard), glycols, isocyanates, ketones. Attacks metals generating flammable hydrogen gas. Attacks some plastics, rubber, and coatings
UN number
ADR/RID: 1764 IMDG: 1764 IATA: 1764
UN proper shipping name
| | ADR/RID: DICHLOROACETIC ACID IMDG: DICHLOROACETIC ACID | |
| IATA: Dichloroacetic acid | ||
| 14.3 | Transport hazard class(es) ADR/RID: 8 IMDG: 8 | IATA: 8 |
| 14.4 | Packaging group ADR/RID: II IMDG: II | IATA: II |
| 14.5 | Environmental hazards ADR/RID: yes IMDG Marine pollutant: yes | IATA: no |
| 14.6 | Special precautions for user No data available | |
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- CAS: Chemical Abstracts Service
- EC50: Effective Concentration 50%
- IATA: International Air Transportation Association
- IMDG: International Maritime Dangerous Goods
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- STEL: Short term exposure limit
- TWA: Time Weighted Average
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
Other Information
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.