Methoxypolyethylene glycol amine is a soluble polymer carrier that can be used in the preparation of polyethylene glycol-containing couplers, in order to enhance their solubility. In addition, it can also be used to prepare Methoxypolyethylene glycol amine-poly(DL-lactic acid) block copolymer (PLA-(MeO-PEG) nanoparticles loaded with PLA-pyrene. The nanoparticles can be effectively delivered to solid tumours. It was also demonstrated that PLA-(MeO-PEG) nanoparticles should be useful drug carriers for passive tumour targeting. Methoxypolyethylene glycol amine is widely used in medical research, drug release, nanotechnology and new materials research, cell culture. Research on active compounds in ligands, peptide synthesis carriers, grafted polymer compounds, new materials, polyethylene glycol modified functional coatings.