Sildenafil VS Tadalafil
Nov 24,2022
Sildenafil
Sildenafil is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Sildenafil (Revatio) is used to improve the ability to exercise in adults with pulmonary arterial hypertension (PAH; excessive blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness). Children should not commonly take sildenafil, but in some cases, a doctor may decide that sildenafil is the best medication to treat a child's condition.
Tadalafil
Tadalafil is used to treat erectile dysfunction (ED, impotence; inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; an enlarged prostate) which includes difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency in adult men. Tadalafil is used to improve the ability to exercise in people with pulmonary arterial hypertension (PAH; excessive blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness).
Both Sildenafil and Tadalafil are in a class of medications called phosphodiesterase (PDE), all treat erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. They also all treat PAH by relaxing the blood vessels in the lungs to allow blood to flow easily.
Although both have a rapid onset of action, Tadalafil works slightly faster than Sildenafil. While Sildenafil normally takes about 20-30 minutes, Tadalafil can work in 15-20 minutes. Tadalafil is also available as Tadalafil Daily, which is taken once a day, and will enable you to achieve an erection anytime throughout the day.
Tadalafil has a longer duration of action than Sildenafil, and can remain in the body for up to 36 hours. This has earned it the reputation of "The Weekend Pill". This benefits you because you don't need to pre-plan your dosage close to any expected sexual activity, but instead can utilise its effects up to 12, and occasionally 36 hours after taking it.
In conclusion, Tadalafil is a more modern, effective treatment for erectile dysfunction. Tadalafil appears to offer advantages over Sildenafil when it comes to the most desirable attributes for an erectile dysfunction medication, including duration of action, onset of action, and side effects.
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Tadalafil is also used to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH). It helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate frequently or urgently (including during the middle of the night). Tadalafil is thought to work by relaxing the smooth muscle in the prostate and bladder.
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Nov 24,2022Organic ChemistryTadalafil
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