Methenolone acetate is an oral anabolic steroid. It is favored by athletes during the fat loss phase of training, when lean tissue growth and toned muscle rather than raw volume are the key goals.

Estrogen side effects

Methenolone acetate is not aromatized by the body and does not produce measurable amounts of estrogen. Antiestrogens are not required when using this steroid, as gynecomastia should not be an issue even in sensitive individuals.

Androgen side effects

Although classified as an anabolic steroid, androgenic side effects of this substance are still common, especially at high doses. This can include oily skin, acne, and body/facial hair growth.

Anabolic/androgenic steroids may also worsen male pattern baldness.

Women are also warned about the potential virilizing effects of anabolic/androgenic steroids. These may include a deepened voice, menstrual irregularities, changes in skin texture, facial hair growth, and clitoral enlargement.

Liver toxicity side effects

Methenolone acetate has no hepatotoxic effects and is therefore unlikely to be hepatotoxic. Although unlikely, hepatotoxicity cannot be completely ruled out, especially at high doses.

Cardiovascular side effects

Anabolic/androgenic steroids can have deleterious effects on serum cholesterol. This includes a tendency to lower HDL (good) cholesterol values and raise LDL (bad) cholesterol values, which may tip the HDL-LDL balance, increasing the risk of changes in the direction of arteriosclerosis.

The relative effects of anabolic/androgenic steroids on lipids depend on dose, route of administration (oral or parenteral), type of steroid (aromatizable or non-aromatizable), and level of resistance to hepatic metabolism.

Due to its non-aromatizable properties, Methenolone acetate should have a stronger negative effect on hepatic cholesterol management than testosterone or nandrolone, but much less than c-17 alpha alkylated steroids. Due to the route of administration, the negative effect of oral primobolone on blood lipids was slightly stronger than that of primobolone enanthate injection.

Anabolic/androgenic steroids may also adversely affect blood pressure and triglycerides, reduce endothelial relaxation, and support left ventricular hypertrophy, all of which may increase the risk of cardiovascular disease and myocardial infarction.

To help reduce cardiovascular stress, it is recommended to maintain an active cardiovascular exercise program and minimize intake of saturated fat, cholesterol, and simple carbohydrates at all times while taking steroids. Fish oil supplementation and natural cholesterol/antioxidant formulas are also recommended.

Testosterone suppression

All anabolic/androgenic steroids are expected to suppress endogenous testosterone production. Testosterone, the major male androgen, provides strong negative feedback on endogenous testosterone production.

Likewise, testosterone-based drugs can have a strong effect on the hypothalamic regulation of natural steroid hormones. In the absence of intervention from testosterone stimulating substances, testosterone levels should return to normal within 1-4 months of discontinuation.

Note that prolonged hypogonadotropic hypogonadism may be secondary to steroid abuse and require medical intervention.