Sodium lauryl ether sulfate (SLES) is relatively safe when used in low doses and is well tolerated by most skin types, including sensitive skin, but some people may experience irritation or sensitivity to this ingredient. In addition, prolonged skin contact with concentrated SLES may cause irritation, and studies have shown that SLES can exacerbate skin irritation, redness, and damage to the skin barrier. Due to its foaming properties, it can cause microscopic tears in the skin barrier, allowing dirt and bacteria to be trapped underneath the barrier, causing acne (just like SLS). Therefore, it is safer in short-term rinseable products and should not exceed 1% in concentrations in products intended for prolonged skin contact.

SLES is a surfactant commonly used in detergent formulations to reduce surface tension between ingredients. It is commonly used as a cleansing and foaming agent in cosmetic formulations to help remove dirt, oil, and impurities from the skin. SLES is milder and less irritating than sodium lauryl sulfate (SLS). It is generally used in shaving cream, lip balm, disinfectant, exfoliant, hand soap, toothpaste, shower gel, bubble bath and other products. Avoid contact with eyes and mouth during use because it is irritating and toxic to the eyes and respiratory tract.

References:

[1] 7 Final Report on the Safety Assessment of Sodium Lauryl Sulfate and Ammonium Lauryl Sulfate[J]. International Journal of Toxicology, 1983, 21 1: 127-181. DOI:10.3109/10915818309142005.