Fludioxonil, developed  by Novartis, is a new type of non-systemic fungicide with epoch-making significance. It is an efficient, safe and new fungicide. It is currently the world's largest-selling seed treatment agent one. Because of its low dosage, minimal toxicity, and long duration, it was rated as a zero-risk product by the US Environmental Protection Agency, and its market prospects are extremely broad.

Toxicity

LD50 (mg/kg) rat (mice) acute oral LD50 male or female>5000, acute oral administration of wild duck and quail>2000, rat acute dermal LD50>2000, this product has no irritation to rabbit eyes and skin . Fish poison (96h, mg/L) LC50 Sunfish 0.31, carp 1.5, rainbow squat fish 0.5, non-toxic to bees, Daphnia LC50 (48h) 1.lmg/L. Test results such as Ames show that it is not teratogenic, non-mutagenic, and non-carcinogenic.

Mechanism of action

By inhibiting the transfer related to the glucose phosphorylation of the bacteria and inhibiting the growth of the fungal mycelium, it will eventually lead to the death of the bacteria. The mechanism of action is unique, and there is no cross-resistance to existing fungicides. Fludioxonil is one of the few products in the world that has received EPA "low risk" certification from the U.S. Environmental Protection Agency.

Application

Fludioxonil is used for the foliar treatment of wheat, barley, corn, peas, rape, rice, vegetables, grapes, lawns, and ornamental crops. It is used to control Fusarium nivalis, Tilletia rot, Rhizoctonia solani, etc. Special effects; treatment of grain and non-grain seeds, prevention and control of seed-borne and soil-borne pathogens, such as Alternaria, Ascodia, Aspergillus, Fusarium, Bipolaris, Rhizoctonia and Penicillium bacteria.