2-Amino-2-methyl-1-propanol: Uses and Toxicity
Nov 24,2022
2-amino-2-methyl-1-propanol appears as a clear light colored liquid. Insoluble in water and about the same density as water. Flash point 172℉.
Uses
2-amino-2-methyl-1-propanol is a substituted aliphatic alcohol and is used majorly as a pH balancer in cosmetic formulations. It is considered safe as currently used in amounts of 2% or less in cosmetic formulas. Aminomethyl propanol can penetrate the skin's uppermost layers, but does not go further, meaning it does not get into the body.
Toxicity
2-amino-2-methyl-1-propanol is of low acute toxicity. The undiluted substance causes corrosion of the eyes and severe skin irritation. In guinea pigs, 2-amino-2-methyl-1-propanol is not sensitizing. After short-term and repeated administration of oral doses of the substance, the liver was shown to be the target organ. The liver-specific serum enzyme activities are increased and histopathological alterations are seen in the liver. 2-Amino-2-methyl-1-propanol can cause damage and haemorrhage in the gastrointestinal mucosa. The hydrochloride is less toxic than the free base.
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2-Amino-2-methyl-1-propanol is used for the preparation of buffer solution and in cosmetics. 2-Amino-2-methyl-1-propanol is also used in ATR-FTIR spectroscopic investigation of the carbon monoxide absorption characteristics.
The passage introduces the differences between 1 Butanol and 2 Butanol, also mentions the intermolecular forces of 2 Butanol.....
Nov 24,2022API2-Amino-2-methyl-1-propanol
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