1-Naphthol: Production and Uses
Nov 18,2022
1-Naphthol is a fluorescent organic compound with the formula C10H7OH. It is a white solid. It has a role as a genotoxin and a human xenobiotic metabolite.
1-Naphthol is used to make dyes, intermediates, synthetic perfumes, agrochemicals, drugs, and rubber antioxidants. It is also used in organic synthesis, photography, hide tanning process, pyrotechnics for black smoke.
Production
One method, Naphthalene is nitrated to give 1-nitronaphthalene, which is hydrogenated to the amine followed by hydrolysis:
C10H8 + HNO3 → C10H7NO2 + H2O
C10H7NO2 + 3H2 → C10H7NH2 + 2H2O
C10H7NH2 + H2O → C10H7OH + NH3
Or, Naphthalene is hydrogenated to tetralin, which is oxidized to 1-tetralone, which undergoes dehydrogenation.
Uses
1-Naphthol is used to make dyes, intermediates, synthetic perfumes, agrochemicals, drugs, and rubber antioxidants. It is also used in organic synthesis, photography, hide tanning process, pyrotechnics for black smoke.
What's more, 1-Naphthol is a precursor to a variety of insecticides including carbaryl and pharmaceuticals including nadolol as well as for the antidepressant sertraline and the anti-protozoan therapeutic atovaquone. It undergoes azo coupling to give various azo dyes, although these are usually less useful than those derived from 2-naphthol.
- Related articles
- Related Qustion
- What are the connections between naphthalene, 1-naphthol (1-NAP) and 2-naphthol (2-NAP) and how to detect 1-NAP and 2-NA Dec 11, 2024
Naphthalene (NAP), 1-naphthol (1-NAP) and 2-naphthol (2-NAP) are bicyclic hydrocarbons (Figure 1) used in the production of dyes, synthetic rubber, pesticides and pharmaceutical industries.
- 1-Naphthol: Natural Occurrence and its Catabolism via Synergistic Regulation May 17, 2024
1-Naphthol, a genotoxin and xenobiotic metabolite, occurs naturally, posing ecological, biochemical, and toxicological implications, crucial for environmental sciences.
- 1-Naphthol: pharmacokinetics, activities and toxicity Jul 12, 2023
1-Naphthol, a compound with antioxidant activity, exhibits first-order kinetics, but oral toxicity studies in mice showed acute toxicity at high doses, leading to mortality and kidney and stom.
Streptomycin sulfate is the sulfate salt form of?streptomycin, an aminoglycoside antibiotic derived from Streptomyces griseus with antibacterial property.....
Nov 18,2022APIThe passage introduces the differences between mineral oil and Synthetic oil.....
Nov 18,2022Organic Solvents1-Naphthol
90-15-3You may like
- 1-Naphthol
-
- $7.00 / 1kg
- 2025-03-13
- CAS:90-15-3
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 10000
- 1-Naphthol
-
- $0.00 / 1KG
- 2025-03-13
- CAS:90-15-3
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 30tons/month
- 1-Naphthol
-
- $1.00 / 25KG
- 2025-03-13
- CAS:90-15-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 2000mt/year