Entranster^TM-R4000是英格恩生物（Engreen Biosystem）最新研發(fā)合成的針對(duì)siRNA、microRNA、mimic、inhibitor、mRNA和shRNA等RNA的轉(zhuǎn)染試劑。Entranster^TM-R4000不僅可以轉(zhuǎn)染小RNA，而且針對(duì)mRNA等長(zhǎng)鏈RNA優(yōu)化。由于納米技術(shù)的應(yīng)用，Entranster^TM-R4000能做到高達(dá)90%的轉(zhuǎn)染效率和60-90%的沉默效率，對(duì)難轉(zhuǎn)染細(xì)胞和原代細(xì)胞也非常適用。

小RNA轉(zhuǎn)染。包括siRNA轉(zhuǎn)染，miRNA，mimic，inhibitor等。 長(zhǎng)鏈的mRNA和shRNA轉(zhuǎn)染，針對(duì)mRNA和長(zhǎng)鏈的shRNA等RNA轉(zhuǎn)染優(yōu)化。 可轉(zhuǎn)染動(dòng)物細(xì)胞、昆蟲(chóng)細(xì)胞等，也可以轉(zhuǎn)染原代細(xì)胞、懸浮細(xì)胞和原代細(xì)胞等傳統(tǒng)難轉(zhuǎn)染細(xì)胞。

納米聚合物，轉(zhuǎn)染效果優(yōu)于脂質(zhì)體轉(zhuǎn)染試劑 高效轉(zhuǎn)染，沉默效率高，可以達(dá)到90％以上的沉默效率 低細(xì)胞毒性，有血清轉(zhuǎn)染，無(wú)須反復(fù)更換培養(yǎng)基 原代細(xì)胞、懸浮細(xì)胞和敏感細(xì)胞都能轉(zhuǎn)。

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   G-MDSC-derived exosomes attenuate collagen-induced arthritis by impairing Th1 and Th17 cell responses.（G-MDSC來(lái)源的外體和膠原誘導(dǎo)的關(guān)節(jié)炎研究）

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   Liraglutide inhibits the apoptosis of human nucleus pulposus cells induced by high glucose through PI3K/Akt/caspase-3 signaling pathway.（利拉魯肽和人髓核細(xì)胞凋亡研究）

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   Targeting the cross-talk between the hedgehog and NF-κB signaling pathways in multiple myeloma.（多發(fā)性骨髓瘤中Hedgehog和NF-κB信號(hào)通路之間的相互作用.）

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