What Is Bacitracin?
Cas number: 1405-87-4
Molecular formula: C66H102N17O16S
Molecular weight: 1421.68538
Bacitracin is a white to off-white fluffy powder. It is soluble in water, ethanol, and pyridine.
It is one of our China GMP-Approved APIs along with Bacitracin zinc, polymyxin b sulfate.
Its acidic or neutral aqueous solution is relatively stable.
When pH maintains at 5-7, its solution is stable for 4 weeks. When solution pH is greater than 9, bacitracin could degrade rapidly at room temperature.
First isolated in 1945 and later commercially produced, bacitracin is a mixture of related polypeptides widely used as an antibiotic in injections or topical formulations.
It is a mixture of related compounds with different antibacterial activities.
Related components include compound A, A1, B, B1, B2, C, D, E, F, G, and X.
Of all those 11 components, compound A was found to have the most antibacterial activity.
Compound B1 and B2 have similar efficacies and are approximately 90% as active as compound A.
The rest of the components do not appear to be extensively studied.
it is an effective narrow-spectrum polypeptide with an antibacterial spectrum similar to penicillin and effective against Gram-positive bacteria, some Gram-negative bacteria, spirochetes, and actinomycetes.
These polypeptides inhibit Gram-positive bacteria by interfering with the cell wall and peptidoglycan synthesis.
Technical Documents Download
COA (Certificate of Analysis)
MOA (Method of Analysis)
MSDS (Material Safety Data Sheet)
HPLC Spectrum (High Performance Liquid Chromatography)
1HNMR Spectrum (1H Nuclear Magnetic Resonance)
13CNMR Spectrum(13C Nuclear Magnetic Resonance)
關鍵字： bacitracin;bacitracin base;桿菌肽;micronizedbacitracin;注射級桿菌肽;
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