expressed with a polyhistidine tag at the C-terminus.
內(nèi)毒素水平:< 1.0 EU per μg of the protein as determined by the LAL method.
緩沖體系:Lyophilized from sterile PBS, pH 7.4.
純化方式:His Tag Purification
產(chǎn)品背景
Angiotensin-converting enzyme 2 (ACE2) is an enzyme attached to the cell
membranesofcellslocatedinthelungs,arteries,heart,kidney,andintestines.
ACE2lowersbloodpressureby catalyzing thehydrolysisof angiotensinIIinto
angiotensin (1–7). ACE2 counters the activity of therelated
angiotensin-convertingenzyme(ACE)by reducingtheamountofangiotensin-II and
increasing Ang(1-7), making it a promising drug target for treating cardiovascular
diseases.ACE2alsoserves asthe entrypointintocellsforsome coronaviruses, including
HCoV-NL63, SARS-CoV, and SARS-CoV-2.
保存條件:Store the product under sterile conditions after opening at -20℃ to -80℃ for 12
months. Avoid repeated freeze-thaw cycles.
運(yùn)輸條件:Liquid product is shipped on dry ice; Lyophilized powder is shipped on ice packs.