鹽酸布替萘芬基本信息MSDS用途與合成方法鹽酸布替萘芬價格(試劑級)上下游產(chǎn)品信息專題中文名稱:鹽酸布替萘芬中文同義詞:鹽酸布替萘芬;鹽酸布替萘酚;N-(4-叔丁基苯基)-N-甲基-1-萘甲胺鹽酸鹽;N-[[4-(1,1-二甲基乙基)苯基]甲基]-N-甲基-1-萘甲胺鹽酸鹽;鹽酸丁萘芬;鹽酸布替萘芬(標(biāo)準(zhǔn)品)英文名稱:Butenafinehydrochloride英文同義詞:kp-363;n-((4-(1,1-dimethylethyl)phenyl)methyl)-n-methyl-1-naphthalenemethanaminehyd;n-((4-(1,1-dimethylethyl)phenyl)methyl)-n-methyl-1-naphthalenemethanaminhy;n-(4-tert-butylbenzyl)-n-methyl-1-naphthalenemethylaminehydrochloride;BUTENAFINEHCL;BUTENAFINEHYDROCHLORIDE;Butenafinehydrochloide;N-(4-t-Butylbenzyl)-N-Methyl-1-naphthalenemethylaminehydrochlorideCAS號:101827-46-7分子式:C23H27N.ClH分子量:353.93EINECS號:642-354-4相關(guān)類別:原料藥;抗病源性微生物藥;抗真菌感染藥物;藥物;中間體;解熱鎮(zhèn)痛類;抗生素;烯丙胺類抗真菌劑;醫(yī)藥原料;小分子抑制劑;抗真菌;抗病毒抗感染類;抗真菌藥;醫(yī)藥抗真菌藥;醫(yī)藥化工類;化工原料;精細化工;中藥對照品;ActivePharmaceuticalIngredients;AntifungalsforResearchandExperimentalUse;Biochemistry;Butenafine;Amines;Aromatics;Inhibitors;Intermediates&FineChemicals;Pharmaceuticals;API;標(biāo)準(zhǔn)品Mol文件:101827-46-7.mol鹽酸布替萘芬性質(zhì)熔點210-214°C儲存條件Refrigerator,UnderInertAtmosphere溶解度DMSO:≥10mg/mL形態(tài)powder顏色whitetooff-whiteMerck14,1518InChIKeyLJBSAUIFGPSHCN-UHFFFAOYSA-NCAS數(shù)據(jù)庫101827-46-7(CASDataBaseReference)鹽酸布替萘芬用途與合成方法化學(xué)性質(zhì)白色結(jié)晶或結(jié)晶性粉末，無臭或略有異臭，味苦。易溶于甲醇、乙醇或氯仿,難溶于無水醋酸或乙腈，幾不溶于乙醚。熔點200～202℃(甲醇-乙酸)。用途烯丙胺類抗真菌劑。有廣譜抗真菌活性。用于皮膚真菌感染，如體部白癬、足部白癬、臀部白癬和花斑糠疹。用途用于治療支氣管哮喘、喘息性支氣管炎和肺氣腫等用途廣譜抗真菌藥，抗病源性微生物藥。用于皮膚真菌感染。治療支氣管哮喘、喘息性支氣管炎和肺氣腫生產(chǎn)方法N-甲基-1-萘甲胺鹽酸和碳酸鈉溶于二甲基甲酰胺，加入對叔丁基芐基溴，在30-40℃下反應(yīng)5h，得鹽酸布替萘芬，收率94%。