Name

Recombinant Human Apo-SAA (Recombinant Human Apolipoprotein-Serum Amyloid A; rHuApo-SAA)；重組人血清淀粉樣蛋白A

Synonyms

SAA; PIG4; SAA2; TP53I4

Purity

>98% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by its ability to down-regulate lipid biosynthesis in aortic smooth muscle cells. The effective concentration was found to be 4μM.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20mM Tris-HCl, pH 9.0, 150mM NaCl.

Endotoxin

N/A

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Others

Background

Serum amyloid A protein which belongs to the SAA family is encoded by the SAA gene in humans. It is expressed by the liver and secreted in plasma. Serum amyloid A is the major acute phase reactant and apolipoprotein of the HDL complex. Elevated serum SAA protein levels may be associated with lung cancer. The level of Apo-SAA, normally 1-5μg/ml in plasma, increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL Apolipoprotein. Recombinant human Apo-SAA1 is an 11.7kDa protein containing 104 amino acid residues.

Amino Acid Sequence

RSFFSFLGEA FDGARDMWRA YSDMREANYI GSDKYFHARG NYDAAKRGPG GVWAAEAISN ARENIQRFFG RGAEDSLADQ AANEWGRSGK DPNHFRPAGL PEKY

產(chǎn)品編號

產(chǎn)品名稱

包裝

KL7282-10μg

Recombinant Human Apo-SAA

10μg

KL7282-50μg

Recombinant Human Apo-SAA

50μg

KL7282-100μg

Recombinant Human Apo-SAA

100μg

KL7282-1mg

Recombinant Human Apo-SAA

1mg

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說明書

1份