Name

Recombinant Human Eotaxin/CCL11 (Recombinant Human Eotaxin/CCL11; rHuEotaxin/CCL11)；重組人嗜酸性粒細(xì)胞趨化因子/CCL11

Synonyms

Eotaxin; C-C motif chemokine 11; chemokine (C-C motif) ligand 11; Eosinophil chemotactic protein; eotaxin; eotaxin-1; MGC22554; SCYA11Small-inducible cytokine A11; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood eosinophils is in a concentration range of 0.1-10.0ng/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH7.4, 150mM NaCl.

Endotoxin

Less than 1EU/μg of rHuEotaxin/CCL11 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

Human CCL11 is belonging to the CC chemokine family. It is encoded by the gene CCL11. CCL11 was first purified from bronchoalveolar lavage fluid of guinea pigs. It was a strong and specific eosinophil chemoattractant in vitro. It can directly chemotactic for eosinophils, but not for monocytes or neutrophils. Human CCL11 is approximately 63% identical at the amino acid level to murine CCL11. In addition, CCL11 also shows about 60% amino acid sequence identity to human MCPs. CCR3 has been identified to be a specific CCL11 receptor.

Amino Acid Sequence

GPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDICADPKKKWVQD SMKYLDQKSP TPKP

產(chǎn)品編號

產(chǎn)品名稱

包裝

KL-6609-5μg

Recombinant Human Eotaxin/CCL11

5μg

KL-6609-20μg

Recombinant Human Eotaxin/CCL11

20μg

KL-6609-100μg

Recombinant Human Eotaxin/CCL11

100μg

KL-6609-1mg

Recombinant Human Eotaxin/CCL11

1mg

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說明書

1份