LEP(116-130)(mouse) 是一種合成的瘦素肽片段。
LEP(116-130)(mouse) is a synthetic leptin peptide fragment.
LEP-(116-130) (300 µM) is unable to inhibit AP-OB binding[1].
LEP-(116-130) (1 mg, i.p.) results in a reduced rate of body weight gain in the presence of increased food intake compared with vehicle-injcted control mice. LEP-(116-130) significantly reduces blood glucose levels by appr 100 mg/dL. Administration of LEP-(116-130) to wild-type (+/+) C57BLKS/J-m mice for 4 or 7 days has no effect on their ability to thermoregulate[1].
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Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2
SCSLPQTSGLQKPES-NH2
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