價格 | 詢價 |
包裝 | 1mg |
最小起訂量 | 1mg |
發(fā)貨地 | 上海 |
更新日期 | 2025-01-14 |
中文名稱:Recombinant Human BD-1, 47a.a. | 英文名稱:Recombinant Human BD-1, 47a.a. |
有效期: 一年 | 產品類別: 重組蛋白 細胞因子 |
產品編號 | 產品名稱 | 產品包裝 | 產品價格 |
P5799-1mg | Recombinant Human BD-1, 47a.a. | 1mg | 15444.00元 |
Species | Gene ID | Accession | Source | Length | MW | Tag |
Human | 1672 | P60022 | E. coli | 47aa | 5.1kDa | - |
About this Antibody | |
Name | Recombinant Human BD-1, 47a.a. (Recombinant Human β-defensin 1, 47a.a.; rHuBD-1, 47a.a.);重組人β-防御素1,47a.a. |
Synonyms | Beta-defensin 1; BD-1; hBD-1; Defensin, beta 1; DEFB1; BD1; HBD1 |
Purity | >98% by SDS-PAGE and HPLC analyses. |
Biological Activity | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using CD34+ dendritic cells is in a concentration range of 100.0-1000.0ng/ml. |
Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
Formulation | Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH7.4, 130mM NaCl. |
Endotoxin | Less than 1EU/μg of rHuBD-1, 47a.a. as determined by LAL method. |
Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. |
Category | Cytokine |
Background | Defensins (alpha and beta) are cationic peptides with antimicrobial activity against Gram-negative and Gram-positive bacteria, fungi, and enveloped viruses. They are 2-6kDa proteins and take important roles in innate immune system. On the basis of their size and pattern of disulfide bonding, mammalian defensins are classified into alpha, beta and theta categories. β-Defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Four human β-defensins have been identified and they are expressed on some leukocytes and at epithelial surfaces. Because β-defensins is cationic peptides, they can therefore interact with the membrane of invading microbes, which are negative due to lipopolysaccharides (LPS) and lipoteichoic acid (LTA) found in the cell membrane. Especially, they have higher affinity to the binding site compared to Ca2+ and Mg2+ ions. Furthermore, they can affect the stability of the membrane. The β-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36a.a.), a propeptide region. Beta-defensin 1 may play a role in the pathogenesis of severe sepsis. Variation in human Beta Defensin-1 contributes to asthma diagnosis, with apparent gender-specific effects. Variation in human β-defensins 1 contributes to asthma diagnosis, with apparent gender-specific effects. Human BD1 is down-regulated in human prostatic and renal carcinomas. |
Amino Acid Sequence | GNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCK |
包裝清單:
產品編號 | 產品名稱 | 包裝 |
P5799-5μg | Recombinant Human BD-1, 47a.a. | 5μg |
P5799-25μg | Recombinant Human BD-1, 47a.a. | 25μg |
P5799-100μg | Recombinant Human BD-1, 47a.a. | 100μg |
P5799-1mg | Recombinant Human BD-1, 47a.a. | 1mg |
- | 說明書 | 1份 |
保存條件:
???????-20℃或更低溫度保存,至少一年有效。由于蛋白的每次凍融均會引起部分失活,所以首次配制成相應濃度的儲存液后(請根據(jù)產品簡介中Reconstitution一欄的信息配制儲存液),須分裝后-20℃或更低溫度凍存,以避免反復凍融。
注意事項:
???????由于有些塑料管壁對某些蛋白有較強的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein,如0.1% BSA等)的主要作用是預先封閉塑料管壁上的蛋白結合位點,使細胞因子或重組蛋白不會粘附于管壁。所以一定要使用產品簡介中Reconstitution一欄的信息配制儲存液。
???????本產品僅限于專業(yè)人員的科學研究用,不得用于臨床診斷或治療,不得用于食品或藥品,不得存放于普通住宅內。
???????為了您的安全和健康,請穿實驗服并戴一次性手套操作。
成立日期 | 2007-07-19 (18年) | 注冊資本 | 1000.000000萬人民幣 |
員工人數(shù) | 500人以上 | 年營業(yè)額 | ¥ 500萬-1000萬 |
主營行業(yè) | 生化試劑,核苷,核苷酸,寡核苷酸,抗體,蛋白組學,生物活性小分子 | 經(jīng)營模式 | 試劑 |
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