Species

Gene ID

Accession

Source

Length

MW

Tag

Rat

25433

Q06175

E. coli

86aa

9.7kDa

－

About this Antibody

Name

Recombinant Rat HB-EGF (Recombinant Rat Heparin-binding EGF-like Growth Factor; rRtHB-EGF)；重組大鼠肝素結(jié)合表皮生長因子樣生長因子

Synonyms

Dtr; Dts; Hegfl; diphtheria toxin receptor (heparin-binding epidermal growth factor-like growthfactor); DTRHEGFLdiphtheria toxin receptor (heparin-binding EGF-like growth factor); DTS; DTSF; heparin-binding EGF-like growth factor; heparin-binding epidermal growth factor; proheparin-binding EGF-like growth factor

Purity

>95% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 1ng/ml, corresponding to a specific activity of >1.0×10⁶IU/mg.

Physical Appearance

Sterile Filtered lyophilized (freeze-dried) liquid-like powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, 300mM NaCl, pH7.4, 5% trehalose.

Endotoxin

Less than 1EU/μg of rRtHB-EGF as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Heparin-binding epidermal growth factor (HB-EGF)-like growth factor (EGF) is found in cerebral neurons. Its expression is increased after hypoxic or ischemic injury, which also stimulates neurogenesis. HB-EGF has been implicated as a participant in a variety of normal physiological processes such as blastocyst implantation and wound healing, and in pathological processes such as tumor growth, SMC hyperplasia and atherosclerosis. HB-EGF is an 87 amino acid mitogenic and chemotactic glycoprotein containing an EGF-like domain with six conserved cysteine residues. In addition, it shares about 73% and 76%a.a. sequence identity with murine and rat HB-EGF.

Amino Acid Sequence

DLEGTDLDLF KVAFSSKPQA LATPGKEKNG KKKRKGKGLG KKRDPCLKKY KDYCIHGECR YLKELRIPSC HCLPGYHGQR CHGLTL

產(chǎn)品編號

產(chǎn)品名稱

包裝

P6384-10μg

Recombinant Rat HB-EGF

10μg

P6384-50μg

Recombinant Rat HB-EGF

50μg

P6384-100μg

Recombinant Rat HB-EGF

100μg

P6384-1mg

Recombinant Rat HB-EGF

1mg

-

說明書

1份