Species

Gene ID

Accession

Source

Length

MW

Tag

Rat

308436

D4A875

E. coli

97aa

11.5kDa

－

About this Antibody

Name

Recombinant Rat VCC-1/CXCL17 (Recombinant Rat VEGF Co-regulated Chemokine 1/CXCL17; rRtVCC-1/CXCL17)；重組大鼠血管內皮生長因子聯(lián)合調節(jié)趨化因子1/CXCL17

Synonyms

CXCL17; DMC; VCC-1; Chemokine (C-X-C Motif) Ligand 17; C-X-C Motif Chemokine 17; Dcip1; Dendritic Cell And Monocyte Chemokine-Like Protein; DMC; UNQ473; VCC1; VCC-1; VEGF Coregulated Chemokine 1; VEGF Co-Regulated Chemokine 1

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by its ability to induce VEGF expression using murine endothelial cells is less than 5.0μg/ml, corresponding to a specific activity of >200IU/mg

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 2X PBS, pH7.4.

Endotoxin

Less than 1EU/μg of rRtVCC-1/CXCL17 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

CXCL17 also named Dendritic Cell and Monocyte Chemokine-like Protein (DMC) and VEGF Co-regulated Chemokine 1 (VCC-1), is a small cytokine belonging to the CXC chemokine family. It is constitutively expressed in the lung and can be detected in trachea, stomach and skeletal muscle. CXCL17 attracts dendritic cells and monocytes and is regulated in tumors. It may be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues and may play a role in the innate defense against infections. Mature human CXCL17 shares 73%, 71% and 64% amino acid sequence identity with bovine, mouse and rat DMC, respectively.

Amino Acid Sequence

SPNQEVARHH GDQHQAPRRW LWEGGQECDC KDWSLRVSKR KTTAVLEPPR KQCPCDHVKG SEKKNRRQKH HRKSQRPSRT CQQFLKRCQL ASFTLPL

產品編號

產品名稱

包裝

P6897-2μg

Recombinant Rat VCC-1/CXCL17

2μg

P6897-10μg

Recombinant Rat VCC-1/CXCL17

10μg

P6897-100μg

Recombinant Rat VCC-1/CXCL17

100μg

P6897-1mg

Recombinant Rat VCC-1/CXCL17

1mg

-

說明書

1份