價格 | 詢價 | ||
包裝 | 100ug | 500ug | 1000ug |
最小起訂量 | 100ug |
發(fā)貨地 | 北京 |
更新日期 | 2024-12-16 |
中文名稱:FZD4蛋白 | 英文名稱:Frizzled-4 |
品牌: 百普賽斯 | 產(chǎn)地: 北京 |
保存條件: -20°C to -70°C | 純度規(guī)格: 99.9% |
產(chǎn)品類別: 重組蛋白 | |
貨號: Frizzled-4 | 用途范圍: 藥物開發(fā)等 |
規(guī)格: 100ug | 是否進口: 否 |
英文名稱:Frizzled-4
中文名稱:卷曲蛋白-4
靶點別稱:FZD4,Frizzled-4,CD344
物種:Human
標簽:Fc Tag
屬性:Protein
標記:Unconjugated
表達區(qū)間及表達系統(tǒng)(Source)
Human Frizzled-4, Fc Tag (FZ4-H5250) is expressed from human 293 cells (HEK293). It contains AA Phe 37 - Glu 180 (Accession # AAI14528).
Predicted N-terminus: Phe 37
蛋白結構(Molecular Characterization)
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 42.9 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重構方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
Frizzled-4(FZD4)也被稱為FzE4、CD344,屬于G蛋白偶聯(lián)受體Fz/Smo家族。大多數(shù)卷曲受體與β-連環(huán)蛋白規(guī)范信號通路偶聯(lián),導致凌亂蛋白的激活、GSK-3激酶的抑制、β-連環(huán)素的核積累和Wnt靶基因的激活。FZD4包含一個FZ(卷曲)結構域。FZD4可能參與組織形態(tài)發(fā)生和/或分化組織中極性信息的轉導和細胞間傳遞。FZD4與MAGI3和去甲靈(NDP)相互作用。
成立日期 | 2010-07-22 (15年) | 注冊資本 | 8000萬人民幣 |
員工人數(shù) | 500人以上 | 年營業(yè)額 | ¥ 1億以上 |
主營行業(yè) | 醫(yī)藥中間體,原料藥,激素類,氨基糖苷類,中樞神經(jīng)系統(tǒng)用藥 | 經(jīng)營模式 | 工廠,試劑 |
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