價格 | ¥12600 |
包裝 | 1mg |
最小起訂量 | 1mg |
發(fā)貨地 | 上海 |
更新日期 | 2024-09-30 |
中文名稱:Transferrin Receptor/TFRC, Human, 重組蛋白 (aa 101-760, His) | 英文名稱:Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His) |
品牌: TargetMol | 產(chǎn)地: 美國 |
保存條件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month | Shipping with blue ice. | 產(chǎn)品類別: 抑制劑 |
貨號: TMPJ-00378 |
名稱 | Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His) |
描述 | Transferrin receptor protein 1 (TFRC) belongs to the peptidase M28 family that is synthesized as a 172 amino acid (aa). TFRC regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. It binds one transferrin or HFE molecule per subunit and binds the HLA class II histocompatibility antigen, DR1. It Interacts with SH3BP3 and STEAP3, facilitates TFRC endocytosis in erythroid precursor cells. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. It positively regulates T and B cell proliferation through iron uptake. |
存儲條件 | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month | Shipping with blue ice. |
關(guān)鍵字 | T 9 | T-9 |
成立日期 | 2013-04-18 (12年) | 注冊資本 | 589.8595萬人民幣 |
員工人數(shù) | 100-500人 | 年?duì)I業(yè)額 | ¥ 1億以上 |
主營行業(yè) | 中間體,天然產(chǎn)物,生物化工,化學(xué)試劑,生物技術(shù)服務(wù) | 經(jīng)營模式 | 貿(mào)易,工廠,試劑,定制,服務(wù) |
產(chǎn)品名稱 | 價格 | 公司名稱 | 報價日期 | |
---|---|---|---|---|
詢價 |
湖北艾普蒂生物工程有限公司
|
2024-02-21 | ||
詢價 |
VIP2年
|
武漢佰樂博生物技術(shù)有限公司
|
2024-11-15 | |
¥2600.00 |
VIP9年
|
北京索萊寶科技有限公司
|
2024-11-16 |