價格 | ¥221 | ¥492 | ¥825 |
包裝 | 1mg | 5mg | 10mg |
最小起訂量 | 1mg |
發(fā)貨地 | 上海 |
更新日期 | 2024-09-29 |
中文名稱:5-乙炔基尿苷 | 英文名稱:5-Ethynyluridine |
CAS:69075-42-9 | 品牌: TargetMol |
產(chǎn)地: 美國 | 保存條件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
純度規(guī)格: 100% | 產(chǎn)品類別: 抑制劑 |
貨號: T36971 |
名稱 | 5-Ethynyluridine |
描述 | 5-Ethynyluridine can be used to label newly synthesized RNA. This approach, named capture of the newly transcribed RNA interactome using click chemistry (RICK), systematically captures proteins bound to a wide range of RNAs, including nascent RNAs and traditionally neglected nonpolyadenylated RNAs. |
體內(nèi)活性 | EU labelling can be used to examine transcription in vivo in mouse models of nervous system disorders. Injection of EU directly into the cerebellum results in reproducible labelling of newly transcribed RNA in cerebellar neurons and glia, with cell type-specific differences in relative labelling intensities, such as Purkinje cells exhibiting the highest levels. EU-labelling accumulating into cytoplasmic inclusions, indicating that EU, like other modified uridines, may introduce non-physiological properties in labelled RNAs[1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMF : 10 mg/mL PBS (pH 7.2) : 5 mg/mL DMSO : 55 mg/mL (205.06 mM) |
關(guān)鍵字 | 5-EU | neurons | purkinje cells | Inhibitor | nascent RNA | 5 Ethynyluridine | RNA transcripts | 5Ethynyluridine | 5-Ethynyluridine | inhibit |
相關(guān)產(chǎn)品 | 5-Fluorouracil | Stavudine |
相關(guān)庫 | 核苷類化合物庫 |
成立日期 | 2013-04-18 (12年) | 注冊資本 | 566.265100萬人民幣 |
員工人數(shù) | 100-500人 | 年營業(yè)額 | ¥ 1億以上 |
主營行業(yè) | 天然產(chǎn)物,生化試劑,分子生物學(xué),分子砌塊,生物技術(shù)服務(wù) | 經(jīng)營模式 | 貿(mào)易,工廠,試劑,定制,服務(wù) |
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