Mouse IFN-alpha 1 Protein, His Tag
分子別名（Synonym）
IFN-alpha 1,IFNA1,IFNalpha 1,IFN-alpha-1,LeIF D
表達區(qū)間及表達系統(tǒng)（Source）
Mouse IFN-alpha 1, His Tag (IFA-M52H3) is expressed from human 293 cells (HEK293). It contains AA Cys 24 - Lys 189 (Accession # P01572-1).
Predicted N-terminus: Cys 24
蛋白結(jié)構(gòu)（Molecular Characterization）
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 21.0 kDa. The protein migrates as 24-27 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內(nèi)毒素（Endotoxin）
Less than 1.0 EU per μg by the LAL method.
純度（Purity）
>90% as determined by SDS-PAGE.
制劑（Formulation）
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重構(gòu)方法（Reconstitution）
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲（Storage）
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景（Background）
干擾素α-1也稱為IFN-α-1/13、干擾素α-D、LeIF D和IFNA1，屬于α/β干擾素家族。干擾素α-1和α-13具有相同的蛋白質(zhì)序列。IFN-α由巨噬細胞產(chǎn)生，具有抗病毒活性。干擾素刺激兩種酶的產(chǎn)生：蛋白激酶和寡腺苷酸合成酶。IFN-α可以抑制或促進自身免疫性糖尿病的發(fā)展。IFN-α很可能在1型糖尿病的病因中起著復雜的作用。
關(guān)鍵字： IFN-alpha 1;IFN-alpha 1蛋白;IFNα1重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group（股票代碼：301080）是成立于2010年的跨國生物科技公司，是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球，橫跨亞洲、北美洲、歐洲，在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務客戶超6000家，與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。