Human STEAP1 Full Length Protein, Twin-Strep,His Tag (Detergent)
分子別名（Synonym）
STEAP1, PRSS24, STEAP
表達(dá)區(qū)間及表達(dá)系統(tǒng)（Source）
Human STEAP1 Full Length Protein, Twin-Strep,His Tag (ST1-H5283) is expressed from human 293 cells (HEK293). It contains AA Glu 2 - Leu 339 (Accession # Q9UHE8-1).
Predicted N-terminus: Met
蛋白結(jié)構(gòu)（Molecular Characterization）
This protein carries a twin strep tag at the N-terminus and a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 44.7 kDa. The protein migrates as 38 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
內(nèi)毒素（Endotoxin）
Less than 1.0 EU per μg by the LAL method.
純度（Purity）
>90% as determined by SDS-PAGE.
制劑（Formulation）
This product is not suitable for cell based experiments due to cytotoxicity of Digitonin.
Digitonin is INDISPENSABLE to keep membrane protein soluble and active, under no circumastance should you remove Digitonin.
Digitonin buffer (DN-12) is sold separately and not included in protein, and please contact us if you need the buffer.
If glycerol is not compatible to your application, remove glycerol just before immediate experiment, and NEVER store glycerol-free protein solution.
Supplied as 0.2 μm filtered solution in 50 mM HEPES, 150 mM NaCl, Digitonin, pH7.5 with glycerol as protectant.
Contact us for customized product form or formulation.
運(yùn)輸（Shipping）
This product is supplied and shipped with dry ice, please inquire the shipping cost.
存儲(chǔ)（Storage）
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
The product MUST be stored at -70°C or lower upon receipt;
-70°C for 3 months under sterile conditions.
背景（Background）
前列腺6跨膜上皮抗原1（STEAP1）是一種完整的膜蛋白，在幾種人類癌癥的細(xì)胞表面高度上調(diào)，使其成為治療這些疾病的有前景的治療靶點(diǎn)。它與催化NADPH依賴性鐵（III）還原的三種酶（STEAP2-STEAP4）具有序列同源性?？紤]到其在人類癌癥中的高特異性和過表達(dá)，STEAP1如今是一種有前景的治療靶點(diǎn)。
關(guān)鍵字： STEAP1;STEAP1蛋白;STEAP1重組蛋白;ACRO;百普賽斯;
百普賽斯集團(tuán)ACROBiosystems Group（股票代碼：301080）是成立于2010年的跨國生物科技公司，是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺(tái)型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團(tuán)業(yè)務(wù)遍布全球，橫跨亞洲、北美洲、歐洲，在中國、美國、瑞士等12個(gè)城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計(jì)服務(wù)客戶超6000家，與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團(tuán)旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。