價(jià)格 | 詢價(jià) | ||
包裝 | 100ug | 500ug | 1000ug |
最小起訂量 | 100ug |
發(fā)貨地 | 北京 |
更新日期 | 2024-12-16 |
中文名稱:Nectin-4蛋白 | 英文名稱:Nectin-4 |
品牌: 百普賽斯 | 產(chǎn)地: 北京 |
保存條件: -20°C to -70°C | 純度規(guī)格: 99.9% |
產(chǎn)品類別: 重組蛋白 | |
貨號(hào): Nectin-4 | 用途范圍: 藥物開(kāi)發(fā)等 |
規(guī)格: 100ug | 是否進(jìn)口: 否 |
分子別名(Synonym)
NECTIN4,LNIR, PRR4, PVRL4
表達(dá)區(qū)間及表達(dá)系統(tǒng)(Source)
Human Nectin-4, His Tag (NE4-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 32 - Ser 349 (Accession # Q96NY8-1).
Predicted N-terminus: Gly 32
蛋白結(jié)構(gòu)(Molecular Characterization)
This protein carries a polyhistidine tag at the C-terminus
The protein has a calculated MW of 36.0 kDa. The protein migrates as 40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(chǔ)(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
Nectin-4(基因名PVRL4,脊髓灰質(zhì)炎病毒受體樣4)是一種66kDa的I型跨膜糖蛋白,屬于Ig超家族蛋白的Nectin家族。凝集素是細(xì)胞粘附分子,在上皮細(xì)胞、內(nèi)皮細(xì)胞、免疫細(xì)胞和神經(jīng)元細(xì)胞的發(fā)育和成年生活中,在各種生物過(guò)程中發(fā)揮關(guān)鍵作用,如極性、增殖、分化和遷移。在50%、49%和86%的乳腺癌、卵巢癌和肺癌中,凝集素-4是一種腫瘤相關(guān)抗原,主要用于預(yù)后不良的腫瘤。在相應(yīng)的正常組織中未檢測(cè)到其表達(dá)。
成立日期 | 2010-07-22 (15年) | 注冊(cè)資本 | 8000萬(wàn)人民幣 |
員工人數(shù) | 500人以上 | 年?duì)I業(yè)額 | ¥ 1億以上 |
主營(yíng)行業(yè) | 醫(yī)藥中間體,原料藥,激素類,氨基糖苷類,中樞神經(jīng)系統(tǒng)用藥 | 經(jīng)營(yíng)模式 | 工廠,試劑 |
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