TNF-beta產(chǎn)品信息
英文名稱:Tumor necrosis factor β
中文名稱:腫瘤壞死因子β
靶點(diǎn)別稱:TNF-beta,Lymphotoxin-alpha
物種:Human
屬性:Protein
標(biāo)記:Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(chǔ)(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
TNF-beta分子背景
TNF-beta是腫瘤壞死因子家族的成員,是淋巴細(xì)胞產(chǎn)生的細(xì)胞因子。該蛋白質(zhì)具有高度的誘導(dǎo)性、分泌性,并與淋巴毒素β形成異三聚體,將淋巴毒素α錨定在細(xì)胞表面。該蛋白還介導(dǎo)多種炎癥、免疫刺激和抗病毒反應(yīng),參與發(fā)育過(guò)程中次級(jí)淋巴器官的形成,并在細(xì)胞凋亡中發(fā)揮作用。該基因的遺傳變異與麻風(fēng)病4型、心肌梗死、非霍奇金淋巴瘤和銀屑病關(guān)節(jié)炎的易感性有關(guān)。或者,已經(jīng)觀察到該基因的剪接轉(zhuǎn)錄變體。
關(guān)鍵字: TNFB蛋白;TNF-beta;TNF-beta蛋白;ACRO;百普賽斯;
百普賽斯集團(tuán)ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國(guó)生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺(tái)型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團(tuán)業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國(guó)、美國(guó)、瑞士等12個(gè)城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計(jì)服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長(zhǎng)期、穩(wěn)定的合作伙伴關(guān)系。集團(tuán)旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。