GM-CSF R alpha產(chǎn)品信息
英文名稱:Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
中文名稱:粒細胞-巨噬細胞集落刺激因子受體α亞基
靶點別稱:GM-CSF R alpha,GM-CSF-R-alpha,GMCSFR-alpha,GMR-alpha,CSF2RA,CSF2R,CSF2RY,CDw116,CD116
物種:Human/Mouse
屬性:Protein
標記:Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
GM-CSF R alpha分子背景
GM-CSF Rα(粒細胞-巨噬細胞集落刺激因子受體亞基α)也稱為CSF2RA、CD116、GMRα。粒細胞-巨噬細胞集落刺激因子低親和力受體。傳遞導(dǎo)致造血細胞增殖、分化和功能激活的信號。遺傳性肺泡蛋白沉積癥(hPAP)是一種罕見的肺表面活性物質(zhì)積聚和低氧性呼吸衰竭疾病,由CSF2RA(編碼粒細胞/巨噬細胞集落刺激因子[GM-CSF]受體α鏈[CD116])突變引起,導(dǎo)致肺泡巨噬細胞對GM-CSF依賴性肺表面活性物質(zhì)的清除減少。
關(guān)鍵字: GM-CSF R alpha;GM-CSF R alpha蛋白;GMCSFRA蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。