IL-17RB產(chǎn)品信息

英文名稱(chēng)：Interleukin-17 receptor B

中文名稱(chēng)：白細(xì)胞介素-17受體B

靶點(diǎn)別稱(chēng)：IL-17 receptor B，IL-17RB

物種：Human

屬性：Protein

標(biāo)記：Unconjugated

內(nèi)毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

純度（Purity）

>95% as determined by SDS-PAGE.

制劑（Formulation）

Lyophilized from 0.22 μm filtered solution in 50 mM Tris,100 mM Glycine,25 mM Arginine,150 mM NaCl,pH7.5 with trehalose as protectant.

Contact us for customized product form or formulation.

重構(gòu)方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存儲(chǔ)（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

IL-17RB分子背景

IL17RB（EVI27，IL17Rh1）是一種單程跨膜受體，屬于IL17R細(xì)胞因子受體家族。發(fā)現(xiàn)它在肝臟、大腦、睪丸和肺部都有表達(dá)。IL17RB的配體是IL17E，也稱(chēng)為IL25。五種IL-17受體（IL17RA-IL17RE）彼此之間表現(xiàn)出相當(dāng)大的序列差異，但似乎都含有由纖維連接蛋白III型（FnIII）結(jié)構(gòu)域組成的細(xì)胞外結(jié)構(gòu)域，以及與Toll/IL-1R（TLR）結(jié)構(gòu)域顯示出松散同源性的細(xì)胞質(zhì)SEF/IL-17R（SEFIR）結(jié)構(gòu)域。