LY75產品信息
英文名稱:Lymphocyte antigen 75
中文名稱:淋巴細胞抗原-75
靶點別稱:LY75,CD205,DEC-205,CLEC13B,Lymphocyte antigen 75,gp200-MR6
物種:Human/Mouse
屬性:Protein
標記:Unconjugated
內毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重構方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
LY75用戶評價
LY75分子背景
淋巴細胞抗原75(Ly 75,也稱為CD205、CLEC13B、GP200-MR6和DEC-205,是一種I型跨膜蛋白,主要在樹突狀細胞和胸腺上皮細胞上表達。LY75作為抗原的內吞受體發(fā)揮作用。MEN1309/OBT076是第一種靶向CD205的抗體藥物,在淋巴瘤中顯示出很強的臨床前抗腫瘤活性。在體內驗證為單一藥物后,抗體-藥物偶聯(lián)物與BCL2抑制劑Venetoclax和抗cd20單克隆抗體利妥昔單抗具有協(xié)同作用。
關鍵字: LY75;LY75蛋白;LY75重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產業(yè)領域提供關鍵生物試劑產品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設有辦公室、研發(fā)中心及生產基地。目前累計服務客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。