Prolactin R產(chǎn)品信息
英文名稱:Prolactin receptor
中文名稱:催乳素受體
靶點(diǎn)別稱:Prolactin R,PRLR,PRL-R
物種:Human
屬性:Protein
標(biāo)記:Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
Prolactin R分子背景
作為一種跨膜受體,催乳素受體(PRL-R)與催乳素相互作用。此外,PRL-R還結(jié)合生長激素(GH)和人胎盤催乳素(hPL)并被其激活。臨床前調(diào)查、流行病學(xué)研究和對患者組織樣本的分析有力地支持催乳素受體(PRLR)信號對乳腺和前列腺腫瘤發(fā)生和癌癥進(jìn)展的貢獻(xiàn)。此外,PRLR已被發(fā)現(xiàn)對妊娠期間乳腺的小葉肺泡成熟至關(guān)重要,PRLR敲除小鼠的小葉肺泡結(jié)構(gòu)發(fā)育嚴(yán)重受損這一事實(shí)證明了這一點(diǎn)。
關(guān)鍵字: Prolactin R;Prolactin R蛋白;催乳素受體;PRLR;PRLR蛋白;
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