| 中文名 | 左旋西孟旦
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| 英文名 | Levosimendan
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| 別名 | 左西孟旦
左旋西孟旦
6-(4-氨基苯基)-5-甲基-4,5-二氫-3(2H)-噠嗪酮
-2-[[4-(1,4,5,6-四氫-4-甲基-6-氧代-3-噠嗪基)苯基]亞肼基]丙二腈
(R)-N-(4-(4-甲基-6-氧代-1,4,5,6-四氫噠嗪-3-基)苯基)羰基亞肼基二氰化物
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| 英文別名 | Simda
Simdax
OR-1259
LEVOSIMENDAN
(R)-Simendan
Levosimendan
Levosimendan [INN]
(R)-2-[[4-(1,4,5,6-TETRAHYDRO-4-METHYL-6-OXO-3-PYRIDAZINYL)PHENYL] HYDROZONO]PRO
((4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono)propanedinitrile
Mesoxalonitrile (p-((R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-pyridazinyl)phenyl)hydrazone
(R)-((4-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono)propanedinitrile
[[4-[(4R)-1,4,5,6-Terahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]hydrazono]propanedinitrile
(R)-((4-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono) propanedintrile
({4-[(4R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl]phenyl}hydrazono)propanedinitrile
Mesoxalonitrile (-)-(p((R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazone
Mesoxalonitrile (-)-{p-[(R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl}hydrazone
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| CAS | 141505-33-1
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| EINECS | 663-528-6 |
| 化學(xué)式 | C14H12N6O
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| 分子量 | 280.28 |
| InChI | InChI=1/C14H12N6O/c1-9-6-13(21)19-20-14(9)10-2-4-11(5-3-10)17-18-12(7-15)8-16/h2-5,9,17H,6H2,1H3,(H,19,21)/t9-/m1/s1 |
| 密度 | 1.33±0.1 g/cm3(Predicted) |
| 熔點(diǎn) | 216-219°C (dec.) |
| 比旋光度 | D25 -566° (tetrahydrofurane/methanol) |
| 溶解度 | DMSO: ≥ 20 mg/mL |
| 折射率 | 1.673 |
| 酸度系數(shù) | 6.3(at 25℃) |
| 存儲(chǔ)條件 | room temp |
| 外觀(guān) | 粉末 |
| 顏色 | yellow |
| 物化性質(zhì) | 熔點(diǎn)210～21413，[α]D25-566°(THF/甲醇，1：1)。 |
| 危險(xiǎn)品標(biāo)志 | Xn - 有害物品
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| 風(fēng)險(xiǎn)術(shù)語(yǔ) | 20/21/22 - 吸入、皮膚接觸及吞食有害。
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| 安全術(shù)語(yǔ) | 36/37 - 穿戴適當(dāng)?shù)姆雷o(hù)服和手套。
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| WGK Germany | 3 |
| RTECS | TY1570210 |
| 上游原料 | 無(wú)水醋酸鈉 丙二腈 |