Product Name:(Cys(Et)2·7)-α-CGRP (human)
CAS No.: 196413-73-7
Synonyms:受體激動劑多肽(Cys(Et)2·7)-α-CGRP
Catalog No.:120P18
Brand:HongTide(上海鴻肽生物)
Description:(Cys(Et)2·7)-α-CGRP (human)是一種有效且有選擇性的CGRP2受體激動劑多肽,序列中含有37個氨基酸。(Cys(Et)2·7)-α-CGRP具有很強的抑制鼠輸精管痙攣反應的功能,其ED50為4-5 nM,盡管在體外生物鑒定中,想要誘導典型的豚鼠心房中CGRP1受體的變時性和變力效果需要很高的濃度(> 1 μM)。
(Cys (Et) 2.7)- α- CGRP (human) is an effective and selective CGRP2 receptor agonist peptide, with a sequence containing 37 amino acids. (Cys (Et) 2.7)- α- CGRP has a strong inhibitory effect on vasospasm in mice, with an ED50 of 4-5 nM. Although in vitro biological identification, high concentrations (>1 μ M) are required to induce the chronotropic and inotropic effects of CGRP1 receptors in typical guinea pig atria.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | AC(Et)DTATC(Et)VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2 |
Sequence(3-letter code) | H-Ala-Cys(Et)-Asp-Thr-Ala-Thr-Cys(Et)-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2 |
Peptide Structure |
|
Molecular Formula | C167H277N51O49S2 |
Molecular Weight | 3847.48 |
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關鍵字: 受體激動劑多肽(Cys(Et)2·7)-;196413-73-7;(Cys(Et)2·7)-α-CGRP ;多肽;多肽合成;
上海鴻肽生物科技有限公司(簡稱:鴻肽生物)是一家以多肽以及多肽上下游產品研發(fā)、生產、銷售以及技術轉讓為主要業(yè) 務科技公司。公司現(xiàn)有產品涵蓋:定制多肽、目錄多肽、氨基酸衍生物、小分子化合物;公司自成立以來,秉持“用質量作船, 以服務為帆,為科研服務”的企業(yè)理念,為國內外眾多科研工作者提供了優(yōu)質的服務及產品。