CD133產(chǎn)品信息
英文名稱(chēng):CD133
中文名稱(chēng):CD133抗原
靶點(diǎn)別稱(chēng):CD133,PROM1,PROML1,Prominin-1,AC133
物種:Human
標(biāo)簽:His Tag
屬性:Protein
標(biāo)記:Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
制劑(Formulation)
This product is not suitable for cell based experiments due to cytotoxicity of DDM.
DDM and CHS are INDISPENSABLE to keep membrane protein soluble and active, under no circumastance should you remove DDM and CHS.
DDM/CHS buffer (DC-11) is sold separately and not included in protein, and please contact us if you need the buffer.
If glycerol is not compatible to your application, remove glycerol just before immediate experiment, and NEVER store glycerol-free protein solution.
Supplied as 0.2 μm filtered solution in 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5 with glycerol as protectant.
Contact us for customized product form or formulation.
運(yùn)輸(Shipping)
This product is supplied and shipped with dry ice, please inquire the shipping cost.
存儲(chǔ)(Storage)
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
The product MUST be stored at -70°C or lower upon receipt;
-70°C for 3 months under sterile conditions.
CD133分子背景
Prominin-1也被稱(chēng)為CD133、抗原AC133、PROM1、PROML1和MSTP061。用作造血干細(xì)胞和祖細(xì)胞(HSPC)的標(biāo)記,用于體干細(xì)胞分離??赡茉诩?xì)胞分化、增殖和凋亡中發(fā)揮作用。將膽固醇結(jié)合在含膽固醇的質(zhì)膜微區(qū)中,并可能在上皮細(xì)胞頂端質(zhì)膜的組織中發(fā)揮作用。在早期視網(wǎng)膜發(fā)育過(guò)程中,它是椎間盤(pán)形態(tài)發(fā)生的關(guān)鍵調(diào)節(jié)因子。參與MAPK和Akt信號(hào)通路的調(diào)控。在神經(jīng)母細(xì)胞瘤中,細(xì)胞以RET依賴(lài)的方式抑制細(xì)胞分化,如神經(jīng)突起的生長(zhǎng)。
CD133用戶(hù)評(píng)價(jià)
關(guān)鍵字: CD133;CD133蛋白;CD133抗原;Prominin-1;CD133重組蛋白;
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