Claudin-6產(chǎn)品信息
英文名稱：Claudin 6
中文名稱：緊密連接蛋白6
靶點(diǎn)別稱：Claudin-6,CLDN6
物種：Human
屬性：Protein / Cell / Antibody Licensing
標(biāo)記：Unconjugated / GFP Fusion
內(nèi)毒素（Endotoxin）
Less than 1.0 EU per μg by the LAL method.
純度（Purity）
>90% as determined by SDS-PAGE.
制劑（Formulation）
Supplied as 0.2 μm filtered solution in 20 mM HEPES, 150 mM NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
運(yùn)輸（Shipping）
This product is supplied and shipped with dry ice, please inquire the shipping cost.
存儲（Storage）
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. The product MUST be stored at -70°C or lower upon receipt;
2. -70°C for 12 months under sterile conditions.
Claudin-6分子背景
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. Claudin-6, also knows as CLDN6, is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. And it is one of the entry cofactors for hepatitis C virus. The methylation of CLDN6 may be involved in esophageal tumorigenesis. The gene of CLDN6 is adjacent to another family member CLDN9 on chromosome 16.
關(guān)鍵字： Claudin 6;Claudin 6蛋白;緊密連接蛋白6;CLDN6;CLDN6蛋白;
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