BAFFR產(chǎn)品信息
英文名稱:B-cell activating factor receptor
中文名稱:B細(xì)胞活化因子受體
靶點別稱:BAFFR,TNFRSF13C,BROMIX,CD268,CVID4,prolixin,BAFF-R
物種:Human / Mouse / Cynomolgus / Rat
屬性:Protein / Kits / Licensing / Antibody Licensin
標(biāo)記:Biotin-labeled / Unconjugated / PE Labeled
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.
BAFFR分子背景
BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.
BAFFR用戶評價
關(guān)鍵字: BAFFR;BAFFR蛋白;BAFFR重組蛋白;B細(xì)胞活化因子受體;TNFRSF13C;
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