Siglec-2產(chǎn)品信息
英文名稱：CD22
中文名稱：CD22
靶點別稱：CD22，SIGLEC2，BL-CAM，SIGLEC-2，Siglec2
物種：Human / Mouse / Rat / Rhesus macaque / Canine
屬性：Protein / Beads / Cell Grade Beads
標(biāo)記：Biotin-labeled / FITC Labeled / Unconjugated / PE Labeled / AF488 Labeled / APC Labeled / AF555 Labeled
內(nèi)毒素（Endotoxin）
Less than 0.1 EU per μg by the LAL method.
無菌（Sterility）
The sterility testing was performed by membrane filtration method.
支原體（Mycoplasma）
Negative.
純度（Purity）
>95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制劑（Formulation）
Lyophilized from 0.22 μm filtered solution in 25 mM MES, 150 mM NaCl, pH5.5 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法（Reconstitution）
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲（Storage）
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.
Siglec-2分子背景
B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Siglec-2用戶評價
關(guān)鍵字： CD22;CD22蛋白;SIGLEC2;SIGLEC2蛋白;CD22重組蛋白;
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