中文名：內(nèi)消旋-2,3-二巰基丁二酸
英文名：meso-2,3-Dimercaptosuccinic acid
中文別名：二巰基丁二酸|DIM-SA|DMS|DMSA|2,3-二硫代-內(nèi)消旋酒石酸
英文別名：Succimer|meso-2,3-Dimercaptosuccinic acid|304-55-2|Dim-sa|meso-Dimercaptosuccinic acid|DMSA|Chemet|(2R,3S)-rel-2,3-Dimercaptosuccinic acid|Succimero|Succimerum|Butanedioic acid, 2,3-dimercapto-, (2R,3S)-rel-|DMS-A|Ro 1-7977|Dimercaptosuccinic acid|(R*,S*)
純度：10mM in DMSO
貨號：M423151
包裝：1ml
Cas號：304-55-2
存儲溫度：-80℃儲存
產(chǎn)品介紹：
DMSA (Meso-2,3-dimercaptosuccinic acid) is a potent lead chelating agent found to be a scavenger of reactive oxygen species (ROS). Murine experiments have shown that this compound also lowers blood pressure in rat arterial hypertension via a decrease in total cell calcium levels. It has also been observed that DMSA upregulates mRNA expression of macrophage-1 antigen, L-, E-, and P-selectin, as well as causing an increase in TNFα (tumor necrosis factor-α) concentrations in murine lung. Mechanistic studies suggest that DMSA is metabolized into mixed disulfides of cysteine, which are active chelating agents.
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關(guān)鍵字： 二巰基丁二酸;DIM-SA;DMS;DMSA
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