中文名：硫鏈絲菌肽
英文名：Thiostrepton
中文別名：硫鏈絲菌素
英文別名：thiostrepton|Thiactin|Bryamycin|1393-48-2|Thiostrepton from Streptomyces azureus|Alaninamide,|NSC81722|NSC 81722|NSC170365|NSC 170365|CHEMBL1981887|CHEBI:94340|AKOS040742575|NCGC00485235-01|Thiostrepton from Streptomyces azureus, >=90% (HPLC)
純度：98%,來(lái)源于Streptomyces laurentii
貨號(hào)：T102394
包裝：1g
Cas號(hào)：1393-48-2
存儲(chǔ)溫度：避光,-20°C儲(chǔ)存,干燥
產(chǎn)品介紹：
Thiostrepton is a cyclic peptide antibiotic, densely packed with thiazoles and other structurally intriguing moieties. Thiostrepton exhibits antibiotic activity throμgh blockade of ribosome turnover after an elongation step in protein synthesis by inhibiting both the dissociation of elongation factor G (EF-G) from the ribosome and the release of inorganic phosphate from EF-G following GTP hydrolysis. Thiostrepton is also described to show efficacy against cancer cell growth throμgh downregulation of the forkhead box M1 (FOXM1) transcription factor, commonly overexpressed in many malignancies. Thiostrepton is an inhibitor of FOXM1A protein synthesis-inhibiting antibiotic
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關(guān)鍵字： 硫鏈絲菌素;thiostrepton;Thiactin;Bryamycin
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