中文名:脫氧核糖核酸酶Ⅱ 來源于豬脾(純化,溶液)
英文名:Deoxyribonuclease II from porcine spleen(Purified,Solution)
中文別名:DNase II;Deoxyribonucleate 3′-oligonucleotido-hydrolase
英文別名:DNase II;Deoxyribonucleate 3′-oligonucleotido-hydrolase
純度:≥12,000 units/mg protein
貨號(hào):D128605
包裝:5ku
Cas號(hào):9025-64-3
存儲(chǔ)溫度:-20°C儲(chǔ)存
產(chǎn)品介紹:
Deoxyribonuclease II from porcine spleen has a molecular weight of 38 kDa. The enzyme is a glycoprotein endonuclease with dimeric structure. Optimum pH range is 4.5-5.0 at ionic strength 0.15 M. Deoxyribonuclease II (Acid DNase) hydrolyzes deoxyribonucleotide linkages in native and denatured DNA yielding products with 3'-phosphates. It also acts on p-nitrophenylphosphodiesters at pH 5.6-5.9. Bernardi (BBRC, 17, 573, 1971) describes a three stage degradation of native DNA by DNase II.DNase II has been used to treat transformed cells during the purification of β-lactamase. It has also been used for the preparation of adenoma tissue in a study that investigated the effect of somatoprim on growth hormone secretion in human adenoma cell cultures (hSA). Deoxyribonuclease II from bovine spleen has been used in a study that conducted a partial purification of deoxyribonucleases from eggs and liver of Xenopus laevis. Deoxyribonuclease II from bovine spleen has also been used in a study to investigate nucleic acid and protein synthesis of splenic lymphocytes.
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關(guān)鍵字: DNase II;Deoxyribonucleate 3′-oligonucleotido-hydrolase;DNase II;Deoxyribonucleate 3′-oligonucleotido-hydrolase
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