中文名：阿西維辛

英文名：Acivicin

英文別名：acivicin|42228-92-2|Antibiotic AT 125|AT-125|Acivicine|AT 125|Acivicino|Acivicinum|NSC-163501|ACIA|NSC 163501|U 42126|U-42,126|NSC163501|(2S)-2-Amino-2-[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]acetic acid|U-42126|(alphaS,5S)-alpha-Amino-3-chloro-2-isoxa

純度：97%

貨號：A134970

包裝：10mg

Cas號：42228-92-2

存儲溫度：-20°C儲存

產品介紹：

An inhibitor of GGT used for solid tumor researchAcivicin is an antineoplastic antibiotic believed to act by interfering with glutamine metabolism which has been administered for research in a variety of solid tumors. Bone marrow depression and central neurotoxicity has been observed to sμggest that it may be dose-limiting. Acivicin is an irreversible inhibitor of GGT (γ-glutamyl transpeptidase) ID50 = 0.54 mM. Additionally, it inhibits the enzymatic conversion of leukotriene C4 to leukotriene D4 and the bioactivation and release of nitric oxide from GSNO6. Also, the product displays anti tumor and anti-metastatic activity and blocks H. Pylori GGT-induced T-cell inhibition.

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