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Recombinant Human TIE2 protein,Recombinant Human TIE2 protein
  • Recombinant Human TIE2 protein,Recombinant Human TIE2 protein

Recombinant Human TIE2 protein 新品

價(jià)格 ￥1950 ￥2890 ￥3760
包裝 50ug 100ug 200ug
最小起訂量 50ug
發(fā)貨地 上海
更新日期 2024-11-07
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產(chǎn)品詳情

中文名稱:Recombinant Human TIE2 protein英文名稱:Recombinant Human TIE2 protein
品牌: 滬震生物產(chǎn)地: 中國(guó)/上海
保存條件: -20°C純度規(guī)格: > 99%
產(chǎn)品類別: 重組蛋白
貨號(hào): HZ502763Q用途范圍: Positive Control; Immunogen; SDS-PAGE; WB
規(guī)格: 10ug 50ug 100ug 200ug 1mg
2024-11-07 Recombinant Human TIE2 protein Recombinant Human TIE2 protein 50ug/1950RMB;100ug/2890RMB;200ug/3760RMB 1950 滬震生物 中國(guó)/上海 -20°C > 99% 重組蛋白

Recombinant Human TIE2 protein

Product Name:Recombinant Human TIE2 protein
Cat No.:HZ502763Q
TargetID:Q02763
Source:E.coli
Gene Accession Number:7010
Peptide Sequence:Met1-Ile465
Tag:N-6His
Purity:> 80%
Formulation:20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Storage Buffer:20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Storage Condition:Aliquot and store at -20??C to -80??C for up to 6 months, buffer containing 7686% glycerol is recomm
Category:Protein
Species Reactivity:Human
Predicted Molecular Mass:55.1kDa
Applications:Positive Control; Immunogen; SDS-PAGE; WB
Background:Tyrosine-protein kinase that acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Has anti-inflammatory effects by preventing the leakage of pro-inflammatory plasma proteins and leukocytes from blood vessels. Required for normal angiogenesis and heart development during embryogenesis. Required for post-natal hematopoiesis. After birth, activates or inhibits angiogenesis, depending on the context. Inhibits angiogenesis and promotes vascular stability in quiescent vessels, where endothelial cells have tight contacts. In quiescent vessels, ANGPT1 oligomers recruit TEK to cell-cell contacts, forming complexes with TEK molecules from adjoining cells, and this leads to preferential activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascades. In migrating endothelial cells that lack cell-cell adhesions, ANGT1 recruits TEK to contacts with the extracellular matrix, leading to the formation of focal adhesion complexes, activation of PTK2/FAK and of the downstream kinases MAPK1/ERK2 and MAPK3/ERK1, and ultimately to the stimulation of sprouting angiogenesis. ANGPT1 signaling triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors. Signaling is modulated by ANGPT2 that has lower affinity for TEK, can promote TEK autophosphorylation in the absence of ANGPT1, but inhibits ANGPT1-mediated signaling by competing for the same binding site. Signaling is also modulated by formation of heterodimers with TIE1, and by proteolytic processing that gives rise to a soluble TEK extracellular domain. The soluble extracellular domain modulates signaling by functioning as decoy receptor for angiopoietins. TEK phosphorylates DOK2, GRB7, GRB14, PIK3R1; SHC1 and TIE1.
Size:10ug  50ug  100ug  200ug  1mg
Synonyms:CD202b; CD202-B; TEK; VMCM1; Tyrosine Kinase With Immunoglobulin Like And EGF Like Domains 2; Venous

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僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！

關(guān)鍵字： CD202b;CD202-B;TEK;VMCM1;Tyrosine ;Kinase;With ;Immunoglobulin ;

公司簡(jiǎn)介

上海滬震實(shí)業(yè)有限公司是一家集研發(fā)、生產(chǎn)和銷售于一體的生命科學(xué)實(shí)驗(yàn)室產(chǎn)品生物科技企業(yè)。主營(yíng)產(chǎn)品：試劑盒，ELISA試劑盒，抗體，重組蛋白，血清，胎牛血清，細(xì)胞，原代細(xì)胞 細(xì)胞培養(yǎng)試劑，常用生化試劑。
成立日期 2014-05-08 （11年） 注冊(cè)資本 100萬(wàn)元整
員工人數(shù) 10-50人 年?duì)I業(yè)額 ￥ 100萬(wàn)以內(nèi)
主營(yíng)行業(yè) 生化試劑,細(xì)胞培養(yǎng),蛋白組學(xué),分子生物學(xué),細(xì)胞生物學(xué) 經(jīng)營(yíng)模式 工廠,試劑,定制,服務(wù)
  • 上海滬震實(shí)業(yè)有限公司
VIP 3年
  • 公司成立：11年
  • 注冊(cè)資本：100萬(wàn)元整
  • 企業(yè)類型：有限責(zé)任公司（國(guó)內(nèi)合資）
  • 主營(yíng)產(chǎn)品：ELISA試劑盒，抗體，細(xì)胞系，原代細(xì)胞，細(xì)胞培養(yǎng)試劑，重組蛋白
  • 公司地址：松江區(qū)
詢盤

Recombinant Human TIE2 protein相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱 價(jià)格   公司名稱 報(bào)價(jià)日期
詢價(jià)
VIP4年
武漢艾美捷科技有限公司
 2024-10-16
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VIP9年
北京索萊寶科技有限公司
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詢價(jià)
VIP5年
湖北惠擇普醫(yī)藥科技有限公司
 2024-11-05
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