Rabbit Anti-Phospho-PDGFRA (Tyr849) / PDGFRB (Tyr857) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-PDGFRA (Tyr849) / PDGFRB (Tyr857)
IR:Immunogen Range:SN(p-Y)VS
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5156
Swiss Prot:P16234
Source:KLH conjugated Synthesised phosphopeptide derived from human PDGF Receptor alpha around the phosphorylation site of Tyr849:SN(p-Y)VS
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The PDGF Receptor Type A (Alpha platelet-derived growth factor receptor precursor, CD140a antigen), a 170kD protein, binds all three isoforms of PDGF with high affinity whereas the PDGF Receptor Type B, a 190kD protein, appears to bind only the PDGF BB homodimer with high affinity. Both receptors are transmembranous, ligand activated protein tyrosine kinases, which phosphorylate a number of important signal transduction proteins, which are bound with differential affinities via SH2 domains. The response of any given cell to PDGF will depend on the types of receptors displayed on the surface and isoforms of PDGF present in the extracellular environment.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
Horse
Sheep
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用!
關(guān)鍵字: Phospho-PDGFRA (Tyr8;PDGF Receptor alpha ;PDGFR A;PDGFR alpha;PDGFR2;PDGFRA;磷酸化血小板源性生長(zhǎng)因子受體α/β抗體;PGFRA_HUMAN;
上海滬震實(shí)業(yè)有限公司是一家集研發(fā)、生產(chǎn)和銷售于一體的生命科學(xué)實(shí)驗(yàn)室產(chǎn)品生物科技企業(yè)。主營(yíng)產(chǎn)品:試劑盒,ELISA試劑盒,抗體,重組蛋白,血清,胎牛血清,細(xì)胞,原代細(xì)胞 細(xì)胞培養(yǎng)試劑,常用生化試劑。