Rabbit  Anti-Bax Monoclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:Bax

IR:Immunogen Range:

Clonality:Monoclonal

Isotype:IgG

Entrez Gene:581

Swiss Prot:Q07812

Source:KLH conjugated synthetic peptide derived from human Bax: 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008].

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
IHC-P(1:100-500)
IHC-F(1:50-200)
ICC(1:100)

Cross Reactive Species:Human
Mouse
Rat

僅供科研使用。不能用于人和動物治療等其它臨床診斷用！