Product Name：ABT-510
CAS No.：442526-87-6
Synonyms：抗血管生成TSP多肽
Catalog No.：218P438
Brand：HongTide（上海鴻肽生物）
Description：ABT-510是一種抗血管生成TSP肽 (thrombospondin-1 類似物)，序列中含有9個(gè)氨基酸，并且包含兩個(gè)非天然氨基酸，能誘導(dǎo)腫瘤細(xì)胞凋亡并抑制上皮性卵巢癌正位、同種異體模型中的卵巢腫瘤生長。ABT-510還可減少小鼠炎癥性腸病模型的血管生成和炎癥反應(yīng)。ABT-510可用于癌癥 (尤其是上皮性卵巢癌) 以及炎癥性腸病 (IBD) 的研究。
ABT-510 is an anti angiogenic TSP peptide (thrombospondin-1 analog) that contains 9 amino acids in its sequence and two unnatural amino acids. It can induce tumor cell apoptosis and inhibit ovarian tumor growth in orthonormal and allogeneic models of epithelial ovarian cancer. ABT-510 can also reduce angiogenesis and inflammatory response in mouse models of inflammatory bowel disease. ABT-510 can be used for research on cancer, especially epithelial ovarian cancer, and inflammatory bowel disease (IBD).
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Ac-Sar-GVIT-Nva-IRP-NHEt |
Sequence(3-letter code) | Ac-Sar-Gly-Val-Ile-Thr-Nva-Ile-Arg-Pro-NHEt |
Peptide Structure | 
|
Molecular Formula | C45H81N13O11 |
Molecular Weight | 980.22 |
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關(guān)鍵字： ABT-510 ;442526-87-6;抗血管生成TSP多肽;多肽;多肽合成;
上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。