Rabbit Anti-phospho-C-Myc (Ser62) Monoclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-C-Myc (Ser62)
IR:Immunogen Range:PL(p-S)PS
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:4609
Swiss Prot:P01106
Source:KLH conjugated Synthesised phosphopeptide derived from human C-Myc around the phosphorylation site of Ser62:PL(p-S)PS
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:50-200)
IHC-F(1:50-200)
ICC(1:50-200)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： phospho-C-Myc (Ser62;C-Myc (Ser62;Myc(Phospho-Ser62);p-Myc(S62);AU016757;MRTL;MGC105490;MYC_HUMAN;
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