Rabbit Anti-Cleaved PARP Monoclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Cleaved PARP
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:142
Swiss Prot:P09874
Source:Recombinant human PARP protein:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IP(1:20-50)
Flow-Cyt(1:50)
ICC(1:50-200)
Cross Reactive Species:Human
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僅供科研使用。不能用于人和動物治療等其它臨床診斷用!
關鍵字: Cleaved PARP;Cleaved ;ADPRT 1;ADPRT;ADPRT1;msPARP;PPOL;PARP1_HUMAN;
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