Rabbit Anti-ABCA1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ABCA1
IR:Immunogen Range:1551-1650/2261
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:19
Swiss Prot:O95477
Source:KLH conjugated synthetic peptide derived from human ABCA1:1551-1650/2261
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. [provided by RefSeq, Sep 2019]
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用!
關(guān)鍵字: ABCA1;ABC1;ABC 1;ABCA 1;ATP binding Cassette;ATP binding cassette;HDLDT1;MGC165011;
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