Rabbit Anti-FOXK1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:FOXK1
IR:Immunogen Range:101-200/733
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:221937
Swiss Prot:P85037
Source:KLH conjugated synthetic peptide derived from human FOXK1:101-200/733
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. In skeletal muscles, undifferentiated myogenic stem cells (satellite cells) can mobilize to regenerate myofibers in response to injury. FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Rabbit
Sheep
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： FOXK1;A630048H08Rik;AI463295;ENSMUSG00000075577;FHX;Forkhead box protein;Gm10868;FOXK1_HUMAN;
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