Rabbit Anti-Phospho-Glycogen synthase 1 (Ser645) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-Glycogen synthase 1 (Ser645)
IR:Immunogen Range:PP(p-S)PS
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2997
Swiss Prot:P13807
Source:KLH conjugated synthesised phosphopeptide derived from human Glycogen synthase 1 around the phosphorylation site of Ser645:PP(p-S)PS
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Glycogen Synthase (GS) is a key enzyme in the regulation of glycogen metabolism. GS catalyzes the incorporation of UDP-glucose incorporation into glycogen. The activity of glycogen synthase is regulated by hormonal stimuli (insulin, catecholamines and glucagons) and non-hormonal stimuli (blood glucose level and exercise). Two main isoforms of mammalian GS are designated as muscle (glycogen synthase 1) and liver (glycogen synthase 2). Most tissues express glycogen synthase 1, whereas glycogen synthase 2 appears to be tissue-specific. The two isoforms have 70% identical amino acid sequence. Glycogen synthase can be phosphorylated by multiple kinases including glycogen synthase kinase-3 (GSK-3), mitogen-activated protein kinase-related protein kinase (DYRK), and SAPK2b/p38b which leads to its inactivation.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Horse
Sheep
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： Phospho-Glycogen syn;Glycogen synthase 1 ;Glycogen synthase 1 ;GSY;GYS1;GYS;EC 2.4.1.11;GYS1_HUMAN;
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