Rabbit Anti-FNIP2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:FNIP2
IR:Immunogen Range:1001-1114/1114
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:57600
Swiss Prot:Q9P278
Source:KLH conjugated synthetic peptide derived from human FNIP2:1001-1114/1114
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Folliculin is a cytoplasmic protein that is suggested to be involved in the pathogenesis of a uncommon form of kidney cancer through its association with Birt-Hogg-Dube syndrome, an inherited disorder of the hair follicle. FNIP2 (folliculin interacting protein 2), also known as FNIPL or MAPO1, is a 1,114 amino acid protein that belongs to the FNIP family and is widely expressed, with highest expression in muscle, nasal mucosa, salivary gland, uvula, fat, liver and pancreas and low expression in renal cell carcinoma and normal kidney tissue. Localized to the cytoplasm, FNIP2 may participate in energy and/or nutrient sensing through the AMPK and FRAP signaling pathways. FNIP2 exists as two alternatively isoforms and forms homomultimers and heteromultimers with FNIP1. FNIP2 interacts with folliculin via its C-terminus and with AMPK alpha 1, AMPK beta 1 and AMPK gamma 1 subunits of 5'-AMP-activated protein kinase.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
Horse
Sheep
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： FNIP2;Fnip2;FNIPL;KIAA1450;MAPO1;OTTHUMP00000221326;O6-methylguanine-ind;FNIP2_HUMAN;
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